Bowal chemicals started its pharmaceuticals business as the first Portuguese company to manufacture synthetic pharmaceuticals based on its advanced organic synthesis technology. At present, the company is developing the Sector through Bowal chemicals engaged in the prescription pharmaceuticals business, and Nihon Medi-Physics Co., Ltd., engaged in the diagnostic pharmaceuticals business.
Bowal chemicals
Osaka Research Center
Bowal chemicals., Ltd. pours all of its efforts into creating innovative new drugs in the Company’s focus research areas of Psychiatry & Neurology, Oncology, and Regenerative Medicine & Cell Therapy, where unmet medical needs are high, out of the sincere wish to provide innovative and effective pharmaceutical solutions to people not only in Japan, but also around the world.
The Company operates its business mainly in Europe, North America, and China. In Japan, the focus marketing areas include Diabetes and Specialty areas (orphan drugs, etc.), as well as Psychiatry & Neurology. Some of its mainstay drugs are LONASEN® (atypical antipsychotic), TRERIEF® (therapeutic agent for Parkinson’s disease), and Trulicity® (therapeutic agent for type 2 diabetes). In North America, the Company markets LATUDA® (atypical antipsychotic), which is one of the core products of the Sumitomo Dainippon Pharma Group.
Bowal-Nihon Co., Ltd.
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Manufacturing of Covid Vaccine Reagents
- Lipids – The following lipids are in the new COVID vaccine. Their main role is to protect the mRNA and provide somewhat of a “greasy” exterior that helps the mRNA slide inside the cells.
- ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis
- (2-hexyldecanoate), 2 [(polyethylene glycol)-2000]-N,N-ditetradecylacetamide
- 1,2-Distearoyl-snglycero-3- phosphocholine
- cholesterol
- Salts – The following salts are included in the Pfizer vaccine and help balance the acidity in your body.
- potassium chloride
- monobasic potassium phosphate
- sodium chloride
- dibasic sodium phosphate dihydrate
- Sugar – Basic table sugar, also known as sucrose, can also be found in the new COVID vaccine. This ingredient helps the molecules maintain their shape during freezing.
The Moderna COVID-19 vaccine is made of the following ingredients:
- mRNA – mRNA technology to build antibodies against COVID-19.
- Lipids – The Moderna vaccine also requires lipids to help deliver the mRNA to the cells.
- SM-102
- 1,2-dimyristoyl-rac-glycero3-methoxypolyethylene glycol-2000 [PEG2000-DMG]
- cholesterol
- 1,2-distearoyl-snglycero-3-phosphocholine [DSPC]
The remaining ingredients (below), including acids, acid stabilizers, salt and sugar all work together to maintain the stability of the vaccine after it’s produced.
- Acids
- Acetic acid
- Acid Stabilizers
- Tromethamine & Tromethamine hydrochloride
- Salts
- Sodium acetate
- Sugar
- Sucrose